The Protein Cost of Metabolic Fluxes: Prediction from Enzymatic Rate Laws and Cost Minimization.

PLoS Comput Biol · 2016 · PMC5094713 · PMID 27812109

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quite significantno p-value reported

Tolerance ranges for nearly optimal solutions Evolution could tolerate non-optimal enzyme costs; this tolerance depends on population dynamics and can sometimes be quite significant, e.g. in small isolated communities.

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