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Premenstrual dysphoric disorder: General overview, treatment strategies, and focus on sertraline for symptom-onset dosing.

Indian J Psychiatry · 2016 · PMC5100127 · PMID 28066013

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near-significantno p-value reported
In summary, symptom-onset treatment with sertraline (50–100 mg/day for about 7 days) was associated with a significant reduction in women's daily record of problem severity (including, specifically, on the anger/irritability subscale), with a significant reduction in depression ratings, and a near-significant reduction in premenstrual tension ratings.

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