Biochemical data: kynurenine pathway changes In the periphery: lungs ( Fig 3A ) IDO1 activity, estimated by the KYN/TRP ratio, tended to be increased in response to UCMS but the difference did not reach statistical significance (p = 0.15).
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Chronic Treatment with the IDO1 Inhibitor 1-Methyl-D-Tryptophan Minimizes the Behavioural and Biochemical Abnormalities Induced by Unpredictable Chronic Mild Stress in Mice - Comparison with Fluoxetine.
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