Vitamin D Status and Virologic Response to HCV Therapy in the HALT-C and VIRAHEP-C Trials.

These associations persisted among European Americans in multivariable adjusted models, with comparable overall odds ratios for high vitamin D status, ≥30 ng/mL, as compared with sufficient vitamin D status, 20 to <30 ng/mL observed for EVR (OR = 0.64, 95% CI = 0.43–0.94) and SVR (OR = 0.49, 95% CI = 0.20–1.17), although there was significant heterogeneity between the two studies for SVR (HALT-C: OR = 0.31, 95% CI = 0.14–0.66; VIRAHEP-C: OR = 0.75, 95% CI = 0.37–1.55) and the overall association did not reach statistical significance ( Table 3 ).

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