Systematic review: genetic biomarkers associated with anti-TNF treatment response in inflammatory bowel diseases.

Aliment Pharmacol Ther · 2016 · PMC5113857 · PMID 27417569

Europe PMC DOI

hedged sentence

0.0850

closest p · 1.7× alpha

0.0850

boldest claim

The sentences

showed a trendP = 0.085so close (0.05 < p ≤ 0.1)

However, analyses of the subgroup with baseline CRP values within the two highest quartiles ( N = 156) showed a trend towards a greater relative change in CRP in the TT carriers [the median decrease of CRP were 80, 77 and 64% among TT, TG and GG genotype carriers ( P = 0.085) after 6 weeks, respectively].

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