marginally significantP =0.056
First, the sex difference in achieving clinical remission during follow-up was statistically significant only in Southern Europe (odds ratio [OR] of female vs male =1.45, P <0.001) and North Africa and the Middle East (OR =1.36, P =0.046) at a significance level of 0.05, and marginally significant at a significance level of 0.1 in Northern Europe (OR =1.15, P =0.056), Central and Eastern Europe (OR =1.19, P =0.057), and also in East Asia (OR =1.30, P =0.077).