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Efficacy and Safety of Direct Oral Anticoagulants Compared to Warfarin in Prevention of Thromboembolic Events Among Elderly Patients with Atrial Fibrillation.

Cureus · 2016 · PMC5115842 · PMID 27900231

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showed a trendno p-value reported
NRS data indicated that DOACs (dabigatran, 110 mg and 150 mg, and rivaroxaban) showed a trend toward a smaller risk of ischemic stroke than warfarin with more benefit in the older elderly than the younger elderly (RRs range: 0.85 - 0.85 and 0.76 - 0.81, respectively) [ 9 ].

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