Effect of endotoxemia in mice genetically deficient in cystathionine-γ-lyase, cystathionine-β-synthase or 3-mercaptopyruvate sulfurtransferase.

Effect of CBS +/− , CSE −/− and Δ3MST on LPS-induced survival Survival curves after LPS challenge tended to be shifted to the right in the CSE −/− and CBS +/− mice compared to the WT mice; however, the effect failed to reach statistical significance, while the survival curves of the WT and Δ3MST mice were superimposable ( Fig. 10 ).

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