Prognostic impact of hormone receptor- and HER2-defined subtypes in inflammatory breast cancer treated with high-dose chemotherapy: a retrospective study.

J Cancer · 2016 · PMC5118671 · PMID 27877223

Europe PMC DOI

hedged sentences

0.0660

closest p · 1.3× alpha

0.0660

boldest claim

The sentences

borderline significancep=0.066so close (0.05 < p ≤ 0.1)

For overall survival, the absence of HER2 overexpression was associated with less favorable OS, with borderline significance (HR=3.67, 95%CI 0.83-16.16, p=0.066).

also in 7,017 other papers

highly significantno p-value reported

Despite these promising results, further confirmed by the PEGASE 07 phase 3 study 11 , highly significant toxicities leading to premature termination of another phase 2 trial (PEGASE 05 study) prevented the integration of HDC-AHSCT as a standard of care 12 .

also in 132,142 other papers

did not reach statistical significanceno p-value reported

In our series TN subtype carried the least favorable prognosis, even though the difference did not reach statistical significance which is consistent with previously known data in IBC or non-IBC patient population 17 , 20 , 21 .

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.