Analysis of ageing-associated grey matter volume in patients with multiple sclerosis shows excess atrophy in subcortical regions.

Neuroimage Clin · 2017 · PMC5121150 · PMID 27896065

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a strong trendno p-value reported

The hippocampus and caudate showed significant excess loss in the younger group ( p < 0.001) and a strong trend in the older-onset group.

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