Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model.

It should be noted, that despite approaching significance and in the same direction for each donor, the reduction in HIV integration by pifithrin-α is modest ( Fig 7F ), and does not correspond entirely to the magnitude of the difference in p24 following reactivation ( Fig 7D ).

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