Isoflurane Exposure Induces Cell Death, Microglial Activation and Modifies the Expression of Genes Supporting Neurodevelopment and Cognitive Function in the Male Newborn Piglet Brain.

Fitting separate models to the data from each region did not show any highly significant results; the largest effect was in the pyriform cortex.

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Using microarray we observed a statistically significant 2.2 fold reduction in the expression of BDNF, although when using qRT-PCR this reduction did not reach statistical significance.

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