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Loss of Cathepsin B and L Leads to Lysosomal Dysfunction, NPC-Like Cholesterol Sequestration and Accumulation of the Key Alzheimer's Proteins.

PLoS One · 2016 · PMC5130271 · PMID 27902765

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The NPC2, but not the NPC1, increase was also observed in Leu/NH 4 Cl-treated cells (although did not reach statistical significance).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.