Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter cohort study.

Arthritis Res Ther · 2016 · PMC5134292 · PMID 27906045

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did not reach statistical significanceno p-value reported

When comparing double-positive patients with triple-positive patients, there was a trend towards a stronger association in triple-positive patients, although this did not reach statistical significance (Fig. 1d ).

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