Variation in the oxytocin receptor gene (OXTR) is associated with differences in moral judgment.

Using linear regression, controlling for population stratification as described above, we found marginally significant associations between the OXTR SNP and the motor impulsiveness subscale of the Barratt Impulsiveness Scale ( β = 0.16, P = 0.037), the Behavioral Inhibition System Scale ( β = 0.164, P = 0.013), two facets of the neuroticism domain of the Five Factor Inventory (NEO-FFI) (impulsiveness: β = 0.143, P = 0.029; self-consciousness: β = 0.128, P = 0.046), as well as total neuroticism score ( β = 0.159, P = 0.014).

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Neither of these effects reached study-wide significance after correction for multiple comparisons using a permutation test. Additionally, we found nominally significant associations between several supplementary self-report measures and AVPR1A rs1042615 or OXTR rs237889 (see Supplementary Table 2 for the full results).

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