Mortality rates of CCR2 -/- (71.4%) and CCR2 -/- →WT (57.1%) mice were significantly higher than that of WT (15.3%; P <0.01 and P <0.05, respectively) but the difference did not reach statistical significance for WT→CCR2 -/- animals (42.8%; P = 0.16).
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Both Cerebral and Hematopoietic Deficiencies in CCR2 Result in Uncontrolled Herpes Simplex Virus Infection of the Central Nervous System in Mice.
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