Barely Significant
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The RAS-Effector Interface: Isoform-Specific Differences in the Effector Binding Regions.

PLoS One · 2016 · PMC5147862 · PMID 27936046

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quite significantno p-value reported
There is, however, a quite significant gap in our understanding of how RAS proteins specifically bind to, and activate, their diverse effectors.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.