Effect of Aclidinium Bromide on Exacerbations in Patients with Moderate-to-Severe COPD: A Pooled Analysis of Five Phase III, Randomized, Placebo-Controlled Studies.

COPD · 2016 · PMC5152596 · PMID 27159613

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did not reach statistical significanceno p-value reported

Similarly, the proportion of patients who experienced ≥1 moderate-to-severe exacerbation was numerically lower with aclidinium compared with placebo in each study; however, these results did not reach statistical significance at the study level or overall ( Table 3 ).

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