Regarding radiation-induced vasculopathy, the Child Cancer Survivor Study reported that tumor relapse, cranial radiotherapy, and concurrent alkylating chemotherapy with radiotherapy are risk factors of stroke.[ 2 ] Moreover, glioma showed a trend toward protection against neurovascular events, however, primitive neuroectodermal tumor showed a trend toward an increased risk.[ 3 ] This is the first case of a radiation-induced aneurysm after radiotherapy with chemotherapy, including an alkylating drug for medulloblastoma, although it is uncertain whether surgical vascular injury, radiotherapy, or chemotherapy alone or in combination were the likely culprits.
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