Comparing expression and activity of PCSK9 in SPRET/EiJ and C57BL/6J mouse strains shows lack of correlation with plasma cholesterol.

Mol Genet Metab Rep · 2017 · PMC5155046 · PMID 27995077

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0.0550

closest p · 1.1× alpha

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boldest claim

The sentences

showed a trendP = 0.055so close (0.05 < p ≤ 0.1)

Compared to the B6 mouse, the SPRET mouse showed a trend towards higher levels of total cholesterol (TC) ( Fig. 1 Aa, P = 0.055), carried significantly higher levels of HDL-C (Fig. 1Ab, P = 0.012) ( Fig. 1 A), but similar levels of LDL-C ( Fig. 1 B, P = 0.295), leading to significantly lower LDL-C/HDL-C ratio ( Fig. 1 C, P < 0.001).

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