Mice were then challenged with the M1 GAS strain (in two separate experiments) and we observed limited reduction in GAS colonies from nasal secretions, in throat, and in Nasal Associated Lymphoid Tissue (NALT; a murine functional homolog to human tonsils) 25 , which did not reach statistical significance ( Supplemental Fig. 1C–H ).
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Novel platform technology for modular mucosal vaccine that protects against streptococcus.
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