Barely Significant
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Randomised clinical trial: exploratory phase 2 study of ONO-2952 in diarrhoea-predominant irritable bowel syndrome.

Aliment Pharmacol Ther · 2017 · PMC5157770 · PMID 27910150

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Results Improvements in irritable bowel syndrome symptoms were seen with ONO ‐2952 over placebo in per‐protocol analyses for all three co‐primary endpoints, but these did not reach statistical significance at the 5% level.

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