Clec11a/osteolectin is an osteogenic growth factor that promotes the maintenance of the adult skeleton.

Micro-CT analysis of L3 vertebrae as a whole, including both cortical and trabecular bone, showed a trend toward reduced bone volume in Clec11a -/- as compared to sex-matched littermate controls, though the difference was not statistically significant ( Figure 2—figure supplement 1M–R ).

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