Although increase in absolute number of the subtype CD3 + /CD8 + T-cell in the PS-LY/CpG group did not reach statistical significance ( P =0.51), it was noticeable compared with that in the PBS group.
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A polyethylenimine-modified carboxyl-poly(styrene/acrylamide) copolymer nanosphere for co-delivering of CpG and TGF-β receptor I inhibitor with remarkable additive tumor regression effect against liver cancer in mice.
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