Missense mutations in the TP53 DNA-binding domain predict outcomes in patients with advanced oral cavity squamous cell carcinoma.

Oncotarget · 2016 · PMC5190089 · PMID 27283772

Europe PMC DOI

hedged sentence

0.0990

closest p · 2.0× alpha

0.0990

boldest claim

The sentences

did not reach statistical significanceP=0.099so close (0.05 < p ≤ 0.1)

However, the survival difference between patients with TP53 DBD missense mutations and all other mutations did not reach statistical significance (P=0.099 and P=0.065 for DFS and DSS, respectively), most likely because of the small sample size (n = 36) of patients harboring all other mutations.

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