nominally significantp = 0.046
For the overall participants, the plasma concentrations of Aβ42 were nominally significant for subjects carrying the rs1784933 G allele having a lower level than those without the G allele ( p = 0.046).
For the overall participants, the plasma concentrations of Aβ42 were nominally significant for subjects carrying the rs1784933 G allele having a lower level than those without the G allele ( p = 0.046).
After adjusting for age, sex, and APOE ε4 allele, the association of the G allele of SORL1 rs1784933 with a lower plasma concentration of Aβ42 remained nominally significant ( p = 0.046); however, the results were only borderline significant for a lower plasma concentration of Aβ40 ( p = 0.071).