A significant trend for increased recurrence risk with increasing number of risk genotypes was observed ( P trend < 0.001); compared with patients in the low-risk group, those in the medium-risk and high-risk groups had approximately 3- and 11-fold increased risks of recurrence, respectively (aHR, 2.7; 95% CI, 1.7–4.2 and aHR, 10.9; 95% CI, 6.8–17.4, respectively).
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Modifying effect of mouse double minute-2 promoter variants on risk of recurrence for patients with squamous cell carcinoma of oropharynx.
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