Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures.

Elife · 2017 · PMC5207770 · PMID 28044981

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0500

boldest claim

The sentences

highly significantp<2×10 −16actually significant

We found 1341 of 4404 that passed QC in our own study (30.4%) were nominally associated with ethnicity (p<0.05), which represented a highly significant (p<2×10 −16 ) enrichment.

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nominally significantp<0.05actually significant

In an earlier study of maternal smoking in Norwegian newborns ( Joubert et al., 2012 ) that identified 26 loci associated with maternal smoking during pregnancy, 19 passed quality control (QC) in our own analysis, and the association between methylation and ethnicity was found to be nominally significant (p<0.05)at 6 (31.6%) CpG loci.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.