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Targeting the MAPK and PI3K pathways in combination with PD1 blockade in melanoma.

Oncoimmunology · 2016 · PMC5215252 · PMID 28123875

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Single BRAFi or MEKi in combination with PD-1 blockade also reduced tumor outgrowth as compared to single BRAFi or MEKi alone, but did not reach statistical significance ( Fig. 2B ).

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