We observed a clear trend towards an increase of dCTP, dTTP and UTP, which was sensitive to A66 (p110α inhibitor) and to a lesser degree to MK-2206 (AKT inhibitor) ( Fig. 5b ).
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Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate.
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