Combination of alpha-synuclein immunotherapy with anti-inflammatory treatment in a transgenic mouse model of multiple system atrophy.

Acta Neuropathol Commun · 2017 · PMC5217191 · PMID 28057080

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Interestingly, the levels of early oligodendroglial precursor cell (OPC) marker Olig2 showed a trend to the increase in tg animals (Additional file 4 ), in line with previous studies reporting an increase in OPC numbers in this mouse model, and a blockage in OPC differentiation [ 9 , 26 ].

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