The right entorhinal cortex showed a trend towards significantly reduced volume in aMCI patients compared with control participants (control: mean = 1177.82, sd = 298.32; aMCI: mean = 1048.93, sd = 336.84; t (75) = 1.76, p = 0.08) but the right hippocampus (control: mean = 3463.67, sd = 508.20; aMCI: mean = 3433.16, sd = 568.60) or hippocampal subregions did not significantly differ in volume between aMCI patients and controls.
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Increased hippocampal activation in ApoE-4 carriers and non-carriers with amnestic mild cognitive impairment.
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