Nrf2 regulates gene-environment interactions in an animal model of intrauterine inflammation: Implications for preterm birth and prematurity.

Notably, among the (phosphate buffered saline (PBS)-treated control mice, Nrf2 −/− mice delivered fewer pups ( Supplementary Figure S1 ) and showed a trend toward reduced pup survival ( Fig. 1b ) compared to WT mice; although, PBS-treated Nrf2 −/− mice exhibited similar birth weights ( Fig. 1c ) and time to delivery as WT mice ( Fig. 1a ).

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