MT5-MMP Promotes Alzheimer's Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking <i>in vitro</i>.

Front Mol Neurosci · 2016 · PMC5223243 · PMID 28119565

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did not reach statistical significanceno p-value reported

Compared to Tg, TgMT5 −/− mice exhibited a 75% significant decrease in the number of plaques (Figures 2A,B ), which were smaller in average (323 ± 57 μm 2 ) compared to Tg (519 ± 122 μm 2 ), although it did not reach statistical significance.

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