Barely Significant
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The efficacy and roles of combining temozolomide with whole brain radiotherapy in protection neurocognitive function and improvement quality of life of non-small-cell lung cancer patients with brain metastases.

BMC Cancer · 2017 · PMC5223345 · PMID 28068937

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showed a trendno p-value reported
RCT showed a trend of toxicities increase compared with RT, however, the toxicities were tolerable and manageable.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.