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CD28/CTLA-4/ICOS haplotypes confers susceptibility to Graves' disease and modulates clinical phenotype of disease.

Endocrine · 2017 · PMC5225215 · PMID 27638540

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When severity and activity status were taken into account, different global haplotypes distribution was seen in case of absence of GO symptoms compared to severity and activity status, but they did not reach statistical significance (in both p corrected = 0.06) (Supplemental Table 14).

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