Reverse Pathway Genetic Approach Identifies Epistasis in Autism Spectrum Disorders.

PLoS Genet · 2017 · PMC5226683 · PMID 28076348

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hedged sentences

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closest p · 0.0× alpha

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boldest claim

The sentences

nominally significantP < 1.0x10 -6actually significant

To individually test candidate SNP pairs for interaction, we tested the nominally significant interaction results ( P < 1.0x10 -6 ) from the PLINK[ 63 , 64 ] epistasis test.

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highly significantno p-value reported

Recent studies in ASDs estimate similarly large contribution of common variants to ASD liability despite inability to identify specific highly significant SNPs[ 4 – 6 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.