Anti-Epileptic Drug Combination Efficacy in an In Vitro Seizure Model - Phenytoin and Valproate, Lamotrigine and Valproate.

PLoS One · 2017 · PMC5226812 · PMID 28076384

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a clear trendno p-value reported

A clear trend towards supra-additive effect was noted (Figs 6 and 7 ).

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did not quite reach statistical significanceno p-value reported

Although there was a trend to increasing suppression of discharges with higher concentrations of VPA, this did not quite reach statistical significance, probably because of the small sample size and inter-trial variability.

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