The CCR2 Inhibitor Propagermanium Attenuates Diet-Induced Insulin Resistance, Adipose Tissue Inflammation and Non-Alcoholic Steatohepatitis.

PLoS One · 2017 · PMC5226841 · PMID 28076416

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.1000

boldest claim

The sentences

borderline significantp = 0.05actually significant

Quantification of inflammatory cell aggregates (a hallmark of NASH) revealed that lobular inflammation was reduced by intervention with propagermanium ( Fig 4C ), with borderline significant effect of early propagermanium treatment ( p = 0.05 for HFD+Pro_6wk and p = 0.18 for HFD+Pro_12wk, respectively).

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did not reach statistical significancep = 0.10so close (0.05 < p ≤ 0.1)

The HFD-induced expression of Tnf-α was diminished in both intervention groups, but this effect did not reach statistical significance ( p = 0.10; HFD vs.

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