Comparative Genome Sequencing Reveals Within-Host Genetic Changes in Neisseria meningitidis during Invasive Disease.

As depicted in Fig 4A only the two blood isolates with either modified Tfp antigenicity (DE10445) or with predicted differences in the Tfp glyosylation status (WUE2121) compared to the corresponding throat isolates had also a slightly decreased serum resistance, although these differences did not reach statistical significance (two-sided t tests with pooled standard deviation from three replicate experiments).

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