Direct Reprogramming of Mouse Fibroblasts toward Leydig-like Cells by Defined Factors.

Stem Cell Reports · 2017 · PMC5233410 · PMID 28017657

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did not reach statistical significancep > 0.05actually significant

Removing each of Ap1 , Dmrt1 , Gata4 , or Nr5a1 significantly decreased the reprogram efficiency while removing each of Nr5a2 , Nr4a1 , Sp1 , Nr0b1 , or Wt1 had the potential to decrease the percentage of mCherry + cells compared with the 11F group, since the differences did not reach statistical significance (p > 0.05).

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