Novel SNPs in <i>IL-17F</i> and <i>IL-17A</i> genes associated with somatic cell count in Chinese Holstein and Inner-Mongolia Sanhe cattle.

J Anim Sci Biotechnol · 2017 · PMC5237346 · PMID 28101335

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0540

boldest claim

The sentences

highly significantP < 0.001actually significant

The results showed that SCC grade had highly significant effect on SCS, IL-17 and IFN-γ in Holstein and on SCS, IL-17 and IL-6 in Sanhe cattle ( P < 0.001).

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tendency towards significanceP = 0.054so close (0.05 < p ≤ 0.1)

The results showed that the combination genotype of SNPs in IL - 17F and IL - 17A were significantly associated with IL-17 cytokine ( P < 0.01) and showed a tendency towards significance for association with SCS ( P = 0.054) in Sanhe cattle. mRNA expression level in different genotypes of IL-17A and its association with IL-4 gene, cytokine IL-4 and SCS The results of qRT-PCR for mRNA expression of IL - 17A and IL - 4 gene showed that mRNA expression of IL - 17A was significantly higher in genotype GG compared with genotype AG (Fig. 2 ).

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