8 , 9 Similarly, there were also two tinzaparin trials that failed to reach statistical significance, one being a large well-powered multinational study that enrolled 900 cancer patients. 10 , 11 The only LMWH to have demonstrated a statistically and clinically meaningful benefit in terms of VTE risk reduction has been dalteparin.
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Dalteparin versus vitamin K antagonists for the prevention of recurrent venous thromboembolism in patients with cancer and renal impairment: a Canadian pharmacoeconomic analysis.
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