Experimental and theoretical investigations into the stability of cyclic aminals.

Beilstein J Org Chem · 2016 · PMC5238614 · PMID 28144295

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a clear trendno p-value reported

Nevertheless, a clear trend can be recognized, indicating that the conformational energy of the ring system is at least an important if not the major contribution to the hydrolytic instability of the investigated systems.

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