Regenerative potential of leucocyte- and platelet-rich fibrin. Part A: intra-bony defects, furcation defects and periodontal plastic surgery. A systematic review and meta-analysis.

The analysis showed no statistical significant difference in PD reduction (mean difference: 0.2 mm, p = 0.2, CI: −0.08 to 0.4), CAL gain (mean difference: 0.4 mm, p = 0.09, CI: −0.06 to 0.8), KTW gain (mean difference: 0.3 mm, p = 0.1, CI: −0.06 to 0.6), tissue thickness (mean difference: 0.2 mm, p = 0.09, CI: −0.03 to 0.4) and root coverage at 6 months (mean difference: 9.6%, p = 0.6, CI: −23.2 to 42.4), although the results showed a trend that L‐PRF was superior for all of these variables.

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