A time course study of Kv1.3 currents in effector memory CD4 T cells showed that Kv1.3 channel numbers increased as soon as 2 hours after activation, reached a peak level at 24 hours and showed a trend to toward decline by 48 hours post-activation ( Fig 6D ).
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T Cell Subset and Stimulation Strength-Dependent Modulation of T Cell Activation by Kv1.3 Blockers.
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