Compared to wild type, Rgs2 -/- animals showed a trend towards increased expression for many cytokines/chemokines, with CCL3, CCL11, CXCL9 and CXCL10 being significantly enhanced.
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Protective Roles for RGS2 in a Mouse Model of House Dust Mite-Induced Airway Inflammation.
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Following HDM instillation, there was a trend towards increased ASM thickness in the Rgs2 -/- animals compared to the wild-type controls, but this failed to reach significance ( Fig 3C , right panel).
While there was a slight trend towards further increased expression in the Rgs2 -/- animals, this was not significant.