Barely Significant
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Metabolic zonation of the liver: The oxygen gradient revisited.

Redox Biol · 2017 · PMC5257182 · PMID 28126520

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quite significantno p-value reported
Thereby, they appear to act in a hierarchical fashion with the gradients of morphogens being basic and the gradients of nutrients, hormones, intrahepatically formed prostanoids, cytokines, and oxygen being modulatory with quite significant impact.

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