Activation and cleavage of SASH1 by caspase-3 mediates an apoptotic response.

Cell Death Dis · 2016 · PMC5260870 · PMID 27831555

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highly significantno p-value reported

6 These data are highly significant for cancer treatment as they suggest that cancer cells with low SASH1 levels might be more resistant to DNA damage-induced apoptosis than cancer cells with higher levels of SASH1.

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did not reach statistical significanceno p-value reported

The proapoptotic gene BAX also showed a decrease following SASH1 knockdown; however, this did not reach statistical significance.

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