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Early Antiretroviral Therapy Is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations.

PLoS Pathog · 2017 · PMC5266327 · PMID 28046096

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Even though some comparisons did not reach statistical significance, effect sizes were medium to large in some cases, supporting that the study was underpowered to answer these questions.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.